Dr. Brian Mayhugh is working hard to solve a problem he kept running into in his career in behavioral health, people not having access to mental healthcare. That problem followed him through four decades of clinical training, healthcare finance, and managed care until he found the piece that changed the math: the teaching core of Cognitive Behavioral Therapy (CBT) could be delivered by technology, consistently and at scale, without sacrificing what the research said actually worked.
MindStreet's Good Days Ahead program, validated across twenty years of academic clinical trials, delivers that gold-standard care at one-fifth the provider time and one-third the cost, with completion rates that outpace traditional face-to-face therapy. The human element of care is still present with the program being administered by doctors, clinicians and other people that care.
Dr. Mayhugh now runs MindStreet Inc. with his father, who is also a psychologist. Together they are focused on bringing their program to large primary care systems — from rural practices to metropolitan primary care waiting rooms — where many people quietly carry their mental health struggles like anxiety and depression alone.
Interview Recorded on: March 20,2026
Dr. Brian Mayhugh is working hard to solve a problem he kept running into in his career in behavioral health, people not having access to mental healthcare. That problem followed him through four decades of clinical training, healthcare finance, and managed care until he found the piece that changed the math: the teaching core of Cognitive Behavioral Therapy (CBT) could be delivered by technology, consistently and at scale, without sacrificing what the research said actually worked.
MindStreet's Good Days Ahead program, validated across twenty years of academic clinical trials, delivers that gold-standard care at one-fifth the provider time and one-third the cost, with completion rates that outpace traditional face-to-face therapy. The human element of care is still present with the program being administered by doctors, clinicians and other people that care.
Dr. Mayhugh now runs MindStreet Inc. with his father, who is also a psychologist. Together they are focused on bringing their program to large primary care systems — from rural practices to metropolitan primary care waiting rooms — where many people quietly carry their mental health struggles like anxiety and depression alone.
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Care at Scale: When Mayhugh implemented Good Days Ahead in study settings, providers spent about one-fifth the time they would in traditional therapy and completion rates ran roughly one and a half times higher than face-to-face sessions, letting one clinician reach far more patients without watering down the care.
Evidence Over Apps: There are thousands of mental health apps, but Mayhugh points to two decades of clinical trials showing Good Days Ahead matches gold-standard CBT with durable results at six months.
Access Everywhere: For a patient two hours from the nearest therapist, Good Days Ahead runs on any internet-connected device and pairs with a telephone or video check-in, so the same rigorous treatment reaches a rural practice that would otherwise mean an eight-hour drive or no care at all.
Meet Our Guest
Dr. Brian Mayhugh
Dr. Brian Mayhugh is the co-founder and CEO of MindStreet Inc., a digital therapeutics company delivering evidence-based, computer-assisted cognitive behavioral therapy. A trained psychologist with a Ph.D. from Fuller Theological Seminary and 35+ years in behavioral health and managed care, he leads the expansion of MindStreet's flagship program, Good Days Ahead — a multimedia CBT program developed with Dr. Jesse Wright of the University of Louisville and Dr. Michael Thase of the University of Pennsylvania — into primary care systems across metropolitan and rural communities.